Πλοήγηση ανά Συγγραφέα "Hurt, E."
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Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export
Grosshans, H.; Deinert, K.; Hurt, E.; Simos, G. (2001)The signal recognition particle (SRP) targets nascent secretory proteins to the ER, but how and where the SRP assembles is largely unknown. Here we analyze the biogenesis of yeast SRP, which consists of an RNA molecule ... -
The cytoplasmic localization of the tRNA aminoacylation cofactor Arc1p depends on Xpo1p-mediated nuclear export
Galani, K.; Hurt, E.; Simos, G. (2003) -
Pus1p-dependent tRNA Pseudouridinylation Becomes Essential When tRNA Biogenesis Is Compromised in Yeast
Großhans, H.; Lecointe, F.; Grosjean, H.; Hurt, E.; Simos, G. (2001)Yeast Pus1p catalyzes the formation of pseudouridine (ψ) at specific sites of several tRNAs, but its function is not essential for cell viability. We show here that Pus1p becomes essential when another tRNA: pseudouridine ... -
The tRNA aminoacylation co-factor Arc1p is excluded from the nucleus by an Xpo1p-dependent mechanism
Galani, K.; Hurt, E.; Simos, G. (2005)Arc1p, a yeast tRNA-binding protein, forms a complex with the aminoacyl-tRNA synthetases, methionyl tRNA synthetase (MetRS) and glutamyl tRNA synthetase (GluRS). Although this complex localizes normally in the cytoplasm, ...